Following numerous leaks, Activision has officially revealed Call of Duty: Ghosts.
This year's entry in the blockbuster FPS series will be made by Infinity Ward and released in November.
It's due to hit Xbox 360, PS3 and PC on November 5, and is also in development for next-generation consoles.
Activision Publishing CEO Eric Hirshberg said: "Infinity Ward set the gold standard for first-person action for a generation, and they're going to do it again with Call of Duty: Ghosts.
"Ghosts delivers an all-new story, all-new characters, an all-new Call of Duty world, all powered by a next generation Call of Duty engine, which is a leap forward for the franchise. Infinity Ward is going all-in to create the next generation of Call of Duty worthy of the world's greatest fans."
Infinity Ward executive producer Mark Rubin added: "Everyone was expecting us to make Modern Warfare 4, which would have been the safe thing to do. But we're not resting on our laurels.
"We saw the console transition as the perfect opportunity to start a new chapter for Call of Duty. So we're building a new sub-brand, a new engine, and a lot of new ideas and experiences for our players. We can't wait to share them with our community."
Activision has also released the first Call of Duty: Ghosts trailer, which promises to deliver an exclusive look at the game at the next-gen Xbox reveal event on May 21.
Major retailers are now taking Call of Duty: Ghosts pre-orders.